Medical Science
获得性血管性血友病综合征
Acquired von Willebrand SyndromeAcquired von Willebrand Syndrome (AvWS) is a rare bleeding disorder characterized by laboratory findings and clinical presentations similar to inherited von Willebrand disease, but occurring in adults without a personal or family history of bleeding diathesis. / 获得性血管性血友病综合征是一种罕见的出血性疾病，其实验室检查结果和临床表现与遗传性血管性血友病相似，但发生在没有个人或家族出血倾向史的成年人中。
- Knowledge type
- 自然理论
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-10-28 21:01:20
Sub-knowledge points
Increased degradation or clearance of circulating vWFAssociated with lymphoproliferative or myeloproliferative disordersAssociated with solid tumors, immunologic and cardiovascular disordersPossible spontaneous clinical and laboratory resolution
Higher-order knowledge points
Bleeding disordersHemostasisLaboratory diagnosis of coagulation
Main parameters and performance indicators
Factor VIII (FVIII) dosage: 血浆中因子VIII的浓度VWF Antigen (vWF:Ag): 血管性血友病因子抗原水平VWF activity (VWF:Ac): 血管性血友病因子活性VWF ristocetin cofactor activity (VWF:RCo): 血管性血友病因子瑞斯托霉素辅因子活性collagen binding assay (CBA): 血管性血友病因子胶原结合试验
Open problems
Confirming the acquired nature of the disorder remains a significant diagnostic challengeManagement is highly individualized and challenging, particularly when discrepancies arise between laboratory findings and the patient's medical history
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Creation and modification trail
1 recordsRecord title: Acquired von Willebrand Syndrome.
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