Chemistry
DNAzyme触发HCR/CRISPR-Cas12a级联
DNAzyme triggered HCR/CRISPR-Cas12a cascadeA dual-mode detection system utilizing a DNAzyme to initiate hybridization chain reaction (HCR) and Cas12a trans-cleavage, enabling ultrasensitive detection of Pb2+. / 一种利用DNAzyme启动杂交链式反应(HCR)和Cas12a反式切割的双模式检测系统，用于超灵敏检测Pb2+。
- Knowledge type
- 工艺技术
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-11-06 17:06:52
Sub-knowledge points
DNAzyme triggerHybridization Chain Reaction (HCR)CRISPR-Cas12a trans-cleavagePb2+ detection
Higher-order knowledge points
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Main parameters and performance indicators
Target: Pb2+Readout: Dual-mode (likely fluorescence and electrochemical)Enzyme: Cas12a
Open problems
No unresolved problem recorded yet
Related literature
ranked by community starsDNAzyme triggered HCR/CRISPR-Cas12a cascade with dual-mode readout for ultrasensitive Pb2+ detectionOpen source
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Creation and modification trail
1 recordsRecord title: DNAzyme triggered HCR/CRISPR-Cas12a cascade.
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