Biosensing
CRISPR/Cas12a-RCA比率传感平台
CRISPR/Cas12a-RCA ratiometric sensing platformA biosensing technology combining CRISPR/Cas12a collateral cleavage activity with Rolling Circle Amplification (RCA) to achieve quantitative detection of specific nucleic acid targets (e.g., microRNA-1281) via a ratiometric optical signal. / 一种结合CRISPR/Cas12a侧切活性与滚环扩增（RCA）的生物传感技术，通过比率光学信号实现特定核酸靶标（如microRNA-1281）的定量检测。
- Knowledge type
- 工艺技术
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-10-22 16:02:53
Sub-knowledge points
CRISPR/Cas12a collateral cleavageRolling Circle Amplification (RCA)Ratiometric sensing
Higher-order knowledge points
No connected node yet
Main parameters and performance indicators
Target: microRNA-1281Enzyme: CRISPR/Cas12aAmplification: Rolling Circle Amplification (RCA)Signal: Ratiometric optical signal
Open problems
No unresolved problem recorded yet
Related literature
ranked by community starsQuantitative detection of the diabetic retinopathy-associated microRNA-1281 via a CRISPR/Cas12a-RCA ratiometric sensing platformOpen source
Related products and links
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Creation and modification trail
1 recordsRecord title: CRISPR/Cas12a-RCA ratiometric sensing platform.
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