Immunology
NLRP3 炎症小体
NLRP3 inflammasomeA multiprotein complex that plays a key role in the innate immune system and the inflammatory response. It is activated by various danger signals and leads to the cleavage of pro-inflammatory cytokines IL-1β and IL-18. / 一种在先天免疫系统和炎症反应中发挥关键作用的多蛋白复合物。它由各种危险信号激活,并导致促炎细胞因子 IL-1β 和 IL-18 的剪切。
- Knowledge type
- 自然理论
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-10-24 17:00:19
Sub-knowledge points
NLRP3 activationIL-18 secretionNeuroinflammation
Higher-order knowledge points
Innate immunityInflammatory response
Main parameters and performance indicators
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Open problems
No unresolved problem recorded yet
Related literature
ranked by community starsMicroglia-targeted delivery of MCC950 suppresses NLRP3–IL-18-mediated neuroinflammation and retinal injury in retinal vein occlusionOpen source
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Creation and modification trail
1 recordsRecord title: NLRP3 inflammasome.
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