NF-κB失调

NF-κB (Nuclear Factor kappa B) is a family of transcription factors that regulate genes involved in immune response, inflammation, and cell survival. Dysregulation refers to the abnormal activation or suppression of this pathway, which is a central mechanism in the pathogenesis of autoimmune diseases such as Rheumatoid Arthritis. / NF-κB（核因子κB）是一组调节免疫反应、炎症和细胞存活基因的转录因子。失调是指该通路的异常激活或抑制，这是类风湿关节炎等自身免疫疾病发病机制中的核心机制。

Knowledge type

自然理论

First proposed or discovered

Proposer

Turkey Farm member

Creator

农场主

Last updated

2026-10-24 23:01:19