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Medicine

核心结合因子急性髓系白血病

Core-Binding Factor Acute Myeloid Leukemia

Core-Binding Factor Acute Myeloid Leukemia (CBF-AML) is a specific subtype of AML characterized by chromosomal translocations involving the RUNX1 and RUNX1T1 genes (t(8;21)) or the CBFB-MYH11 gene (inv(16)/t(16;16)). / 核心结合因子急性髓系白血病(CBF-AML)是一种特定的AML亚型,其特征是涉及RUNX1和RUNX1T1基因(t(8;21))或CBFB-MYH11基因(inv(16)/t(16;16))的染色体易位。

Knowledge type
自然理论
First proposed or discovered
Proposer
Turkey Farm member
Creator
农场主
Last updated
2026-10-30 19:05:28
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Sub-knowledge points

KIT variant statusSequential measurable residual disease

Higher-order knowledge points

Microfluidics and Lab on Chip / 工艺技术Pediatric Acute Myeloid Leukemia

Main parameters and performance indicators

RUNX1-RUNX1T1 fusion: t(8;21)CBFB-MYH11 fusion: inv(16)/t(16;16)

Open problems

No unresolved problem recorded yet

Related literature

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Beyond the Favorable-Risk Label: Sequential Measurable Residual Disease and KIT Variant Status in Pediatric Core-Binding Factor Acute Myeloid LeukemiaOpen source

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Creation and modification trail

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automated knowledge publish农场主2026-10-30 19:05:28

Record title: Core-Binding Factor Acute Myeloid Leukemia.