Biomedical Engineering
芯片肝脏
Liver-on-ChipA microfluidic device that integrates living cells and microstructures to mimic the physiological microenvironment of the liver, enabling more accurate in vitro studies of liver structure, function, and disease. / 一种集成活细胞和微结构的微流控装置,用于模拟肝脏的生理微环境,从而能够更准确地体外研究肝脏的结构、功能和疾病。
- Knowledge type
- 物理设备
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-10-30 19:05:29
Sub-knowledge points
Organoids3D-bioprinted constructsMulti-organ-on-chip
Higher-order knowledge points
Main parameters and performance indicators
microfluidic channels: mimic blood flowmulticellular architecture: includes hepatocytes and other cell typesextracellular matrix (ECM): provides structural support and biochemical cuesbiophysical and biochemical parameters: replicate in vivo conditions
Open problems
Long-term stability and scalabilityIntegration with multi-organ systemsStandardization of protocols
Related literature
ranked by community starsAdvanced In Vitro Platforms for Experimental Liver Research: From Organoids and Liver‐on‐Chip to Omics and Artificial IntelligenceOpen source
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Creation and modification trail
1 recordsRecord title: Liver-on-Chip.
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