Biomedical Engineering
微针透皮给药系统
Microneedle-based transdermal drug delivery systemsA method of administering drugs through the skin using arrays of micron-sized needles that bypass the stratum corneum barrier. / 一种利用微米级针阵列将药物递送至皮肤的方法，该技术可绕过角质层屏障。
- Knowledge type
- 实际应用
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-11-13 22:05:54
Sub-knowledge points
Hollow microneedles for continuous infusionSolid microneedles for pretreatment (pro-drug delivery)Dissolving microneedles for single-use applications
Higher-order knowledge points
Semiconductor fabrication and lithography / 工艺技术Transdermal drug delivery
Main parameters and performance indicators
Needle length: Typically 50-2000 micrometers to target the epidermis or upper dermisMaterial: Biodegradable polymers (e.g., PLGA) or metals (e.g., stainless steel)Fabrication strategy: Micromolding, laser ablation, or etching
Open problems
Long-term stability of drug formulations within the microneedlesScalable manufacturing for clinical-grade devicesStandardization of clinical translation protocols
Related literature
ranked by community starsMicroneedle-based transdermal drug delivery systems: Types, fabrication strategies and clinical translationOpen source
Related products and links
Microneedle patchesDissolving microneedle arrays
Creation and modification trail
1 recordsRecord title: Microneedle-based transdermal drug delivery systems.
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