Microfluidics and Lab on Chip
实验室一体化系统
Lab-in-a-Tube SystemA diagnostic platform integrating hierarchically wrinkled electrodes and DNAzyme-functionalized beads within a tubular flow cell for enrichment-free detection of pathogens. / 一种集成分级皱纹电极和DNAzyme功能化微珠的管式流动诊断平台，用于无需富集的病原体检测。
- Knowledge type
- 实际应用
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-11-14 18:07:33
Sub-knowledge points
Redox RNA-cleaving DNAzymesAntifouling magnetic beadsTubular flow cellHierarchically structured sensing electrodes
Higher-order knowledge points
Point-of-care diagnosisInfectious disease detectionClostridioides difficile infection diagnosis
Main parameters and performance indicators
Hierarchical electrodes: Enhance reporter capture efficiencyDNAzyme-functionalized beads: Provide RNA cleaving catalytic activityLimit of detection: 1.3 × 10^2 CFU mL^-1
Open problems
Matrix-associated interferents can destabilize DNAzymesNonspecific binding in complex biological matrices
Related literature
ranked by community starsLab‐in‐a‐Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme‐Functionalized Beads for Diagnosis of Clostridioides difficile InfectionOpen source
Related products and links
Lab-in-a-Tube diagnostic platform
Creation and modification trail
1 recordsRecord title: Lab-in-a-Tube System.
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