biomedical engineering
pH响应性注射用玉米醇溶蛋白杂化软骨体水凝胶
pH-responsive injectable zein hybrid chondrosomal hydrogelA biomaterial construct designed for the localized, controlled release of amlodipine in breast cancer treatment. It utilizes a zein-based hydrogel matrix that undergoes structural changes in response to pH levels, facilitating the targeted delivery of the drug to the tumor microenvironment. / 一种用于乳腺癌治疗局部、可控释放氨氯地平的生物材料构建体。它利用基于玉米醇溶蛋白的水凝胶基质，该基质对pH水平产生结构变化，促进药物向肿瘤微环境的靶向递送。
- Knowledge type
- 物理设备
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-11-15 21:06:09
Sub-knowledge points
Zein hybrid chondrosomal hydrogelAmlodipine therapyBreast cancer treatment
Higher-order knowledge points
No connected node yet
Main parameters and performance indicators
pH responsiveness: triggers drug release in acidic tumor environmentsZein matrix: biodegradable and biocompatible polymer baseAmlodipine: the repurposed therapeutic agent encapsulated within the hydrogel
Open problems
No unresolved problem recorded yet
Related literature
ranked by community starsEngineering a pH-responsive injectable zein hybrid chondrosomal hydrogel for enhanced repurposed amlodipine therapy in breast cancer: Integrated in-vitro, in-vivo and in-silico evaluationsOpen source
Related products and links
Amlodipine-loaded hydrogel
Creation and modification trail
1 recordsRecord title: pH-responsive injectable zein hybrid chondrosomal hydrogel.
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