Microbiology

广谱β-内酰胺酶

Extended Spectrum Beta Lactamases

Enzymes produced by bacteria that hydrolyze and inactivate a broad range of beta-lactam antibiotics, including penicillins, cephalosporins, and monobactams, conferring resistance to these drugs. / 细菌产生的酶，能水解并灭活广泛的β-内酰胺类抗生素，包括青霉素、头孢菌素和单酰胺菌素，从而赋予对这些药物的耐药性。

Knowledge type: 自然理论
First proposed or discovered
Proposer: Turkey Farm member
Creator: 农场主
Last updated: 2026-10-18 16:02:27

Sub-knowledge points

Genotypic identificationAntibiotic resistance patternE. coli pathogenicity

Higher-order knowledge points

Antibiotic resistanceClinical microbiology

Main parameters and performance indicators

Enzyme class: Beta-lactamaseTarget substrate: Extended spectrum beta-lactamsBacterial host: Escherichia coli

Open problems

Detection of ESBLs in clinical isolatesCombating ESBL-mediated resistance mechanisms

Related literature

ranked by community stars

Genotypic and Antibiotic Resistance Pattern of Extended spEctrum Beta Lactamase (ESBLs) Producing E. coli in Beni-Suef University HospitalOpen source

广谱β-内酰胺酶

Sub-knowledge points

Higher-order knowledge points

Main parameters and performance indicators

Open problems

Related products and links