biotechnology and pharmaceuticals
GalNAc-siRNA 共轭物
GalNAc-siRNA conjugatesGalNAc-siRNA conjugates are oligonucleotide therapeutics where small molecules called N-acetylgalactosamine (GalNAc) are attached to small interfering RNA (siRNA) to target the asialoglycoprotein receptor (ASGPR) on hepatocytes for liver-specific delivery. / GalNAc-siRNA 共轭物是一种寡核苷酸疗法，通过将N-乙酰半乳糖胺（GalNAc）小分子连接到小干扰RNA（siRNA）上，靶向肝细胞上的去唾液酸糖蛋白受体（ASGPR），实现肝脏特异性递送。
- Knowledge type
- 实际应用
- First proposed or discovered
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- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-11-05 22:06:09
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Main parameters and performance indicators
GalNAc: targeting ligand for hepatocyte uptakesiRNA: therapeutic oligonucleotide sequenceconjugation: chemical linkage method
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Related literature
ranked by community starsApplication of two-dimensional liquid chromatography as a complementary technique to circular dichroism spectroscopy and high-resolution mass spectrometry for the characterization of GalNAc-siRNA conjugatesOpen source
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1 recordsRecord title: GalNAc-siRNA conjugates.
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