Microfluidics and Lab on Chip
流体动力细胞捕获与释放微流控芯片
Hydrodynamic Cell Capture and Release Microfluidic ChipA microfluidic device designed for cancer drug screening that utilizes a direction-sensitive microstructure with adaptive flow resistance regulation. It integrates a concentration gradient generator, trap array, and flow resistance-regulating microchannels to achieve efficient cell capture and release by switching driving directions. / 一种用于癌症药物筛选的微流控装置，利用具有自适应流阻调节的方向敏感微结构。它集成了浓度梯度发生器、陷阱阵列和流阻调节微通道，通过切换驱动方向实现高效细胞捕获与释放。
- Knowledge type
- 物理设备
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-11-12 20:06:22
Sub-knowledge points
Direction-sensitive microstructureConcentration gradient generatorTrap arrayFlow resistance-regulating microchannels
Higher-order knowledge points
Microfluidic chip-based drug screeningCell capture efficiency: 92.0 ± 4.4%Cell release efficiency: 70.0 ± 8.6%
Main parameters and performance indicators
channel width: determines cell capture and release efficienciesnilotinib concentration: used for drug screening (10.79 μM IC50)flow resistance: adaptive regulation between forward and reverse modes
Open problems
No unresolved problem recorded yet
Related literature
ranked by community starsHydrodynamic Cell Capture and Release Microfluidic Chip for Cancer Drug ScreeningOpen source
Related products and links
Microfluidic device
Creation and modification trail
1 recordsRecord title: Hydrodynamic Cell Capture and Release Microfluidic Chip.
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