Clinical Hematology
狼疮抗凝物检测
Lupus Anticoagulant TestingA laboratory test used to detect lupus anticoagulants (LA), which are antibodies that interfere with phospholipid-dependent clotting assays. The test typically employs two phospholipid-dependent clotting assays, such as LA-sensitive activated partial thromboplastin time (aPTT). / 一种用于检测狼疮抗凝物（LA）的实验室检测方法，这是一种干扰磷脂依赖性凝血试验的抗体。该检测通常使用两种磷脂依赖性凝血试验，如LA敏感的活化部分凝血活酶时间（aPTT）。
- Knowledge type
- 实际应用
- First proposed or discovered
- Proposer
- Turkey Farm member
- Creator
- 农场主
- Last updated
- 2026-11-15 17:05:45
Sub-knowledge points
Staclot-LA assayFully automated coagulation analyserSemi-automated coagulation analyserSTA-R-Max analyser
Higher-order knowledge points
Phospholipid-dependent clotting assaysActivated partial thromboplastin time (aPTT)Coagulation analyser
Main parameters and performance indicators
LA-sensitive aPTT: A phospholipid-dependent clotting assay used for detectionHexagonal phase phospholipids: Reagent component used in the Staclot-LA assayInternal Quality Controls (IQC): Staclot-LA1/LA2 for reproducibility assessmentExternal Quality Assurance (EQA): Probioqual and ECAT programs for inter-laboratory comparison
Open problems
Increasing biases of clotting time differences observed in LA positive samples between automated and semi-automated analysers
Related literature
ranked by community starsPerformance Assessment of Staclot‐LA Assay on Fully Automated Coagulation Analyser for Lupus Anticoagulant Testing Using Internal and External Quality ControlsOpen source
Related products and links
Staclot-LA assayStaclot-LA1Staclot-LA2
Creation and modification trail
1 recordsRecord title: Lupus Anticoagulant Testing.
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