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Immunology

NLRP3 炎症小体

NLRP3 inflammasome

A multiprotein complex that plays a key role in the innate immune system and the inflammatory response. It is activated by various danger signals and leads to the cleavage of pro-inflammatory cytokines IL-1β and IL-18. / 一种在先天免疫系统和炎症反应中发挥关键作用的多蛋白复合物。它由各种危险信号激活,并导致促炎细胞因子 IL-1β 和 IL-18 的剪切。

Knowledge type
自然理论
First proposed or discovered
Proposer
Turkey Farm member
Creator
农场主
Last updated
2026-10-24 17:00:19
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Sub-knowledge points

NLRP3 activationIL-18 secretionNeuroinflammation

Higher-order knowledge points

Innate immunityInflammatory response

Main parameters and performance indicators

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Open problems

No unresolved problem recorded yet

Related literature

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Microglia-targeted delivery of MCC950 suppresses NLRP3–IL-18-mediated neuroinflammation and retinal injury in retinal vein occlusionOpen source

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Creation and modification trail

1 records
automated knowledge publish农场主2026-10-24 17:00:20

Record title: NLRP3 inflammasome.