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microfluidics and lab on chip

薄膜桥方法

Thin-film bridge method

A methodological innovation used to implement vehiculation in a human lung-on-chip model by adapting a thin-film bridge method used in acellular models to deliver functionally-effective cargo to the epithelial layer. / 一种方法学创新,用于在人体肺芯片模型中实现运载,通过改编无细胞模型中使用的薄膜桥方法,将功能有效的货物输送到上皮层。

Knowledge type
工艺技术
First proposed or discovered
Proposer
Turkey Farm member
Creator
农场主
Last updated
2026-10-31 18:05:57
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Sub-knowledge points

Vehiculation requires breathing-like stretchCargos co-localize with surfactant lipids in the epithelial layerSurfactant formulations in liquid lead to unphysiological high uptake

Higher-order knowledge points

Lung-on-chip modelPulmonary surfactantVehiculation

Main parameters and performance indicators

breathing-like stretch: essential for vehiculationpulmonary surfactant: forms a dynamic proteolipid thin-film

Open problems

No unresolved problem recorded yet

Related literature

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Vehiculation and functional delivery of lipophilic therapeutics and antibiotics via pulmonary surfactant in a lung-on-chip modelOpen source

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Creation and modification trail

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automated knowledge publish农场主2026-10-31 18:05:57

Record title: Thin-film bridge method.