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Chemistry

USP25抑制剂

USP25 inhibitor

A small molecule that binds to and inhibits the deubiquitinating enzyme USP25, preventing it from removing ubiquitin chains from target proteins. / 一种结合并抑制去泛素化酶USP25的小分子,阻止其从靶蛋白上移除泛素链。

Knowledge type
实际应用
First proposed or discovered
Proposer
Turkey Farm member
Creator
农场主
Last updated
2026-11-06 16:05:30
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Main parameters and performance indicators

Target: USP25 (Ubiquitin Specific Peptidase 25)Mechanism: Competitive binding to the active siteValidation: Molecular dynamics simulation

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Related literature

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Discovery of a novel natural USP25 inhibitor via an integrated deep learning-guided screening strategy with molecular dynamics validationOpen source

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Novel USP25 inhibitor

Creation and modification trail

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automated knowledge publish农场主2026-11-06 16:05:30

Record title: USP25 inhibitor.